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Cognitive ability in children with chronic granulomatous disease: a comparison of those managed conservatively with those who have undergone hematopoietic stem cell transplant.

Abstract
Chronic granulomatous disease (CGD) is a primary immunodeficiency managed conservatively or with hematopoietic stem cell transplant. Studies have shown people with CGD and those transplanted for primary immunodeficiencies have lower than average cognitive ability. In this study, IQ in children with CGD and those transplanted for it was within the normal range.
AuthorsTheresa S Cole, Fiona McKendrick, Andrew J Cant, Mark S Pearce, Catherine M Cale, David R Goldblatt, Andrew R Gennery, Penny Titman
JournalNeuropediatrics (Neuropediatrics) Vol. 44 Issue 4 Pg. 230-2 (Aug 2013) ISSN: 1439-1899 [Electronic] Germany
PMID23397467 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
CopyrightGeorg Thieme Verlag KG Stuttgart · New York.
Topics
  • Cognition Disorders (etiology, surgery)
  • Granulomatous Disease, Chronic (complications, surgery)
  • Hematopoietic Stem Cell Transplantation (methods)
  • Humans
  • Ireland
  • Male
  • Neuropsychological Tests
  • Treatment Outcome
  • United Kingdom

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