Abstract |
The "gold standard" of the prevention of atrial fibrillation related thromboembolic events is anticoagulation therapy with oral vitamin K antagonists. A certain proportion of high-risk patients with atrial fibrillation are not receiving effective antithrombotic therapy because of problems associated with its use. Resolution of subsequent left atrial appendage thrombi is quite a great challenge in patients who are not tolerating "standard" antithrombotic drugs. According to the knowledge of the authors, this is the first report of a patient with non-valvular persistent atrial fibrillation and high stroke risk, who was intolerant to "standard" anticoagulant therapy and had persistent left atrial appendage thrombi following the use of a wide variety of "standard" anticoagulants. Successful resolution of left atrial appendage thrombi with dabigatran and successful percutaneous left atrial appendage closure were performed in this case.
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Authors | Zsuzsanna Kis, Csaba Földesi, Mátyás Pál, Zoltán Som, Andrea Csillik, Pál Abrahám, András Temesvári, Géza Fontos, András Szatmári, Péter Andréka, Attila Kardos |
Journal | Orvosi hetilap
(Orv Hetil)
Vol. 154
Issue 7
Pg. 262-5
(Feb 17 2013)
ISSN: 0030-6002 [Print] Hungary |
Vernacular Title | Percutan bal pitvari fülcsezárás dabigatrannal való fülcsethrombus feloldását követÅ‘en. |
PMID | 23395790
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Anticoagulants
- Antithrombins
- Benzimidazoles
- Heparin, Low-Molecular-Weight
- beta-Alanine
- Dabigatran
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Topics |
- Anticoagulants
(administration & dosage)
- Antithrombins
(therapeutic use)
- Atherectomy
- Atrial Appendage
(diagnostic imaging, pathology)
- Atrial Fibrillation
(diagnostic imaging, therapy)
- Benzimidazoles
(therapeutic use)
- Comorbidity
- Dabigatran
- Echocardiography, Transesophageal
- Female
- Heparin, Low-Molecular-Weight
(administration & dosage)
- Humans
- Middle Aged
- Obesity, Morbid
(complications)
- Risk Factors
- Stroke
(prevention & control)
- Thrombosis
(diagnostic imaging, drug therapy)
- Treatment Outcome
- beta-Alanine
(analogs & derivatives, therapeutic use)
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