Hepatic encephalopathy in a liver transplant recipient with stable liver function.

Postshunt hepatic encephalopathy after liver transplantation (LT) is an infrequent condition and is commonly associated with portal occlusion or stenosis and the presence of a patent portosystemic shunt. Portal vein stenosis (PVS) or thrombosis (PVT) are uncommon complications after LT. The overall frequency of both complications is reported to be less than 3%. When PVS or PVT develop early after LT, the occlusion of the portal vein can have catastrophic consequences to the graft including acute liver failure and graft loss. Late PVT/PVS are asymptomatic in approximately 50% of the cases and mainly diagnosed by a routine ultrasound. Symptomatic postshunt hepatic encephalopathy (HE) is a very infrequent condition after LT that has been scarcely reported in the literature. We present here the case of a liver recipient with normal graft function who presented with hepatic encephalopathy 3 months after LT with stable liver function but a severe portal stenosis and the presence of a spontaneous portosystemic shunt whose successful endovascular treatment was followed by the complete resolution of the HE.
AuthorsJuan Pablo Arab, Luis Meneses, Rosa M Pérez, Marco Arrese, Carlos Benítez
JournalHepatology (Baltimore, Md.) (Hepatology) Vol. 57 Issue 4 Pg. 1672-4 (Apr 2013) ISSN: 1527-3350 [Electronic] United States
PMID23390114 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
  • Constriction, Pathologic (complications, physiopathology, surgery)
  • Endovascular Procedures
  • Hepatic Encephalopathy (diagnosis, etiology)
  • Humans
  • Liver (physiology)
  • Liver Cirrhosis (surgery)
  • Liver Transplantation
  • Male
  • Middle Aged
  • Portal System (physiopathology)
  • Treatment Outcome

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