Oxybutynin treatment for hyperhidrosis: a comparative analysis between genders.

Abstract

OBJECTIVE:

To assess the results of palmar and axillary hyperhidrosis treatment in males and females using low doses of oxybutynin.

METHODS:

A retrospective analysis was conducted in 395 women and 170 men followed up in our service with complaint of palmar and axillary hyperhidrosis.

RESULTS:

A total of 70% of patients in both groups presented partial or great improvement in the level of hyperhidrosis after treatment. The best results were obtained in the female group, in which 40% classified their improvement as "great". Approximately 70% of the patients in both groups improved their quality of life after medical therapy and 30% presented no change in condition.

CONCLUSION:

Gender is not a factor that significantly interferes in oxybutynin treatment results. Quality of life indices and clinical improvement level were similar in men and women.

• Authors: Nelson Wolosker, Mariana Krutman, Taiz Pereira Donozo Almeida Campdell, Paulo Kauffman, Jose Ribas Milanez de Campos, Pedro Puech-Leão
• Journal: Einstein (Sao Paulo, Brazil) (Einstein (Sao Paulo)) 2012 Oct-Dec Vol. 10 Issue 4 Pg. 405-8 ISSN: 2317-6385 [Electronic] Brazil
• PMID: 23386077 (Publication Type: Journal Article)

Chemical References

• Mandelic Acids
• Muscarinic Antagonists
• oxybutynin

Topics

• Adolescent
• Adult
• Aged
• Axilla
• Chi-Square Distribution
• Child
• Child, Preschool
• Female
• Hand
• Humans
• Hyperhidrosis (drug therapy, psychology)
• Male
• Mandelic Acids (administration & dosage, adverse effects)
• Middle Aged
• Muscarinic Antagonists (administration & dosage, adverse effects)
• Quality of Life
• Retrospective Studies
• Sex Factors
• Treatment Outcome
• Xerostomia (chemically induced)
• Young Adult