Abstract | OBJECTIVE: STUDY DESIGN: Sixty patients, aged 12-18, with orthodontic fixed appliances were randomly assigned into three groups as follows: Group 1 (n=20): 1% chlorhexidine and 1% thymol varnish (CervitecPlus); Group 2 (n=20): CervitecPlus+ 0.2% chlorhexidine and 0.2% sodium fluoride (900 ppm fluoride) (CervitecGel)); and Group 3 (n=20): 0.1% fluoride varnish ( Fluor Protector). Mutans streptococci (MS), lactobacilli (LB) levels, buffering capacity (BC), visible plaque index (VPI), and gingival bleeding index (GBI) scores were evaluated at four stages: T0, before orthodontic bonding; T₁, one week after orthodontic bonding; T₂, one week; and T₃, four weeks after the first application, respectively. Inter and intra group comparisons were made by the Kruskal-Wallis, Mann-Whitney U, Friedman and Wilcoxon Signed-Rank tests with Bonferroni step-down correction (P<0.017). RESULTS: Significantly lower MS and LB levels were found in Group 2 than Group 1 (T₂) and 3 (T₂, T₃) (P<0.017). Groups 1-2 (T₂) showed significantly higher BC (P<0.017) and lower VPI and GBI (P<0.017) scores compared with Group 3. Decreased MS levels at T₂ (P<0.017) and T₃ (P>0.017) were found in Group1-2 compared with T0. Significantly lower LB levels were recorded in Group 2 at T₂ compared with T₀ (P<0.017) while no significant differences were seen in Group 1 and 3 (P>0.017). CONCLUSIONS: Addition of CervitecPlus+CervitecGel combination to the standard oral hygiene regimen may be beneficial for orthodontic patients for maintaining oral health by reducing bacterial colonisation and gingivitis.
|
Authors | Ozgul Baygin, Tamer Tuzuner, Mehmet-Birol Ozel, Ozge Bostanoglu |
Journal | Medicina oral, patologia oral y cirugia bucal
(Med Oral Patol Oral Cir Bucal)
Vol. 18
Issue 2
Pg. e362-70
(Mar 01 2013)
ISSN: 1698-6946 [Electronic] Spain |
PMID | 23385499
(Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)
|
Chemical References |
- Anti-Infective Agents, Local
- Drug Combinations
- Fluorides, Topical
- Toothpastes
- chlorhexidine, thymol drug combination
- Thymol
- Fluorides
- Chlorhexidine
|
Topics |
- Adolescent
- Anti-Infective Agents, Local
(therapeutic use)
- Child
- Chlorhexidine
(therapeutic use)
- Dental Caries
(prevention & control)
- Drug Combinations
- Fluorides
(therapeutic use)
- Fluorides, Topical
(therapeutic use)
- Humans
- Office Visits
- Orthodontics, Corrective
- Prospective Studies
- Single-Blind Method
- Thymol
(therapeutic use)
- Toothpastes
|