Abstract | BACKGROUND: Radiation-induced angiosarcomas are uncommon adverse sequelae related to treatment of tumors. Early diagnosis and treatment are key to successful management. PURPOSE: The purpose of this case study is to describe the clinical characteristics of radiation-induced angiosarcomas. MATERIALS AND METHODS: We retrospectively reviewed the medical literature using PubMed, searching the terms angiosarcoma, breast, post, radiation, and treatment. Patient reports and previous reviews of the subject were critically assessed and the salient features are presented. RESULTS: CONCLUSION: We recommend that new skin lesions within or adjacent to radiation ports should be considered for biopsy. Also, for lesions that are larger, ill-defined, or both, several sites should be sampled to ensure an accurate diagnosis and to prevent the possibility of a false negative interpretation.
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Authors | C Lane Anzalone, Philip R Cohen, Abdul H Diwan, Victor G Prieto |
Journal | Dermatology online journal
(Dermatol Online J)
Vol. 19
Issue 1
Pg. 2
(Jan 15 2013)
ISSN: 1087-2108 [Electronic] United States |
PMID | 23374944
(Publication Type: Case Reports, Journal Article)
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Topics |
- Adult
- Biopsy
- Breast Neoplasms
(pathology)
- Female
- Hemangiosarcoma
(etiology, pathology)
- Humans
- Middle Aged
- Neoplasms, Radiation-Induced
(pathology)
- Neoplasms, Second Primary
(pathology)
- Skin Neoplasms
(etiology, pathology)
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