Abstract | BACKGROUND: Treatment of hookworm-related cutaneous larva migrans (HrCLM) with a single dose of oral ivermectin has not been adequately evaluated to date. Response rates reported in three large studies varied from 77% to more than 95%. OBJECTIVES: We evaluated the efficacy of ivermectin in the treatment of HrCLM. METHODS: We retrospectively studied all returning travellers with HrCLM who consulted in our institution. Patients were then treated with a single, 200 μg/kg dose of ivermectin, orally. RESULTS: Sixty-two travellers (35 female, 27 male, mean age 35.6 years) with HrCLM and creeping dermatitis were included. Six patients (10%) also had associated hookworm folliculitis. Fifty-nine patients (95%) completely responded with one ivermectin dose. The response rate was 98% in the 56 patients presenting with only creeping dermatitis and 66% in the six patients presenting with additional hookworm folliculitis (P = 0.02). CONCLUSION:
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Authors | C Vanhaecke, A Perignon, G Monsel, S Regnier, F Bricaire, E Caumes |
Journal | Journal of the European Academy of Dermatology and Venereology : JEADV
(J Eur Acad Dermatol Venereol)
Vol. 28
Issue 5
Pg. 655-7
(May 2014)
ISSN: 1468-3083 [Electronic] England |
PMID | 23368818
(Publication Type: Journal Article)
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Copyright | © 2013 The Authors Journal of the European Academy of Dermatology and Venereology © 2013 European Academy of Dermatology and Venereology. |
Chemical References |
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Topics |
- Adolescent
- Adult
- Aged
- Anthelmintics
(therapeutic use)
- Child
- Child, Preschool
- Female
- Hookworm Infections
(drug therapy)
- Humans
- Ivermectin
(therapeutic use)
- Male
- Middle Aged
- Skin Diseases, Parasitic
(drug therapy)
- Young Adult
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