Abstract | OBJECTIVE: METHODS: Totally 197 KOA outpatients [including wind-cold-damp retention syndrome (50 cases, 61 knees), yang deficiency cold coagulation syndrome (48 cases, 58 knees), stagnation of blood stasis syndrome (49 cases, 63 knees), and insufficiency of Shen-essence syndrome (50 cases, 66 knees)] were treated with warm needling therapy, 10 days as one therapeutic course, 3 courses in total. The symptom score and changes of clinical efficacy were assessed. The contents of interleukin-1 (IL-1), interleukin-6 (IL-6), and tumor necrosis factor-alpha ( TNF-alpha) in the synovial fluid were determined before and after treatment. RESULTS: The symptom scores and the clinical efficacy were improved in all syndrome groups after treatment (P < 0.05), with the best effects shown in the yang deficiency cold coagulation syndrome (P < 0.05) and the worst effects shown in the stagnation of blood stasis syndrome (P < 0.05). The contents of IL-1, IL-6, and TNF-alpha in the synovial fluid decreased after treatment in all syndrome groups (P < 0.05), with the best effects shown in the yang deficiency cold coagulation syndrome (P < 0.05). CONCLUSION:
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Authors | Kun-Da Hong, Li Li, Xi-Hai Li |
Journal | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine
(Zhongguo Zhong Xi Yi Jie He Za Zhi)
Vol. 32
Issue 11
Pg. 1466-9
(Nov 2012)
ISSN: 1003-5370 [Print] China |
PMID | 23359965
(Publication Type: English Abstract, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- IL6 protein, human
- Interleukin-1
- Interleukin-6
- Tumor Necrosis Factor-alpha
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Topics |
- Acupuncture Therapy
(methods)
- Adult
- Aged
- Female
- Humans
- Interleukin-1
(analysis)
- Interleukin-6
(analysis)
- Male
- Medicine, Chinese Traditional
- Middle Aged
- Osteoarthritis, Knee
(diagnosis, therapy)
- Synovial Fluid
(chemistry)
- Tumor Necrosis Factor-alpha
(analysis)
- Yang Deficiency
(therapy)
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