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Fragile X syndrome therapeutics: translation, meet translational medicine.

Abstract
Fragile X syndrome, a common cause of intellectual disability and autism, is thought to occur due to abnormal regulation of neuronal protein synthesis. A study by Osterweil et al. (2013), in this issue, demonstrates that the HMG-CoA reductase inhibitor lovastatin can normalize protein synthesis and also reduce audiogenic seizures in Fmr1 knockout mice.
AuthorsJonathan Lipton, Mustafa Sahin
JournalNeuron (Neuron) Vol. 77 Issue 2 Pg. 212-3 (Jan 23 2013) ISSN: 1097-4199 [Electronic] United States
PMID23352156 (Publication Type: Comment, Journal Article)
CopyrightCopyright © 2013 Elsevier Inc. All rights reserved.

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