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[Orbital tumor--hemangiopericytoma--in a neonate].

AbstractPURPOSE:
To present a case of Haemangiopericytoma (HPC), a rare neopalsm which originates from the vascular pericytes. HPC occurs most commonly in adults. Only 5-10% of cases occur in children. Congenital orbital HPC is generally unknown in the field of ophthalmology.
MATERIAL AND METHODS:
A case of congenital, large exophthalmus is reported in a 1 day old male neonate. Imaging studies demonstrated a vascular, orbital mass involving skull base and cranial fossa.
RESULTS:
The diagnosis of HPC was established after histological exmination. Lesion did not qualify to surgical resection. The child was treated with chemotherapy for 10 months and a great regression of tumor was noted. There was no tumor recurrence during 4 years of a follow up.
CONCLUSIONS:
Chemotherapy may have a significant role in the treatment of infants with nonoperative malignant hemangiopericytoma.
AuthorsBarbara Chipczyńska, Mirosława Grałek
JournalKlinika oczna (Klin Oczna) Vol. 114 Issue 2 Pg. 124-6 ( 2012) ISSN: 0023-2157 [Print] Poland
Vernacular TitleGuz oczodołu--haemangiopericytoma--u noworodka.
PMID23346800 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Dactinomycin
  • Vincristine
  • Cyclophosphamide
Topics
  • Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
  • Child, Preschool
  • Cranial Fossa, Posterior (diagnostic imaging)
  • Cyclophosphamide (therapeutic use)
  • Dactinomycin (therapeutic use)
  • Exophthalmos (congenital)
  • Follow-Up Studies
  • Hemangiopericytoma (congenital, diagnosis, drug therapy, pathology)
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Orbital Neoplasms (congenital, diagnosis, drug therapy, pathology)
  • Radiography
  • Remission Induction
  • Skull Base Neoplasms (congenital, diagnosis, drug therapy, pathology)
  • Vincristine (therapeutic use)

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