Abstract | PURPOSE: METHODS: In order to ascertain the clinical significance of PlGF expression in colorectal cancer, the researcher analyzed the expression pattern of PlGF by using an immunohistochemical method and attempted to establish if a relationship existed between PlGF expression and microvessel density (MVD), and subsequently between PlGF expression and the predicted prognosis. A total of 83 patients with colorectal cancer were included for immunohistochemical staining. Clinicopathological characteristics were defined according to the tumor-node- metastasis (TNM) criteria of the Union for International Cancer Control. Clinicopathologic factors, such as age, sex, histological types of tumors, tumor cell grade, TNM stage, lymphovascular invasion, and lymph-node metastasis, were reviewed. RESULTS: In this study, the PlGF protein expression level was significantly correlated with MVD, patient survival, and clinicopathological factors such as lymph-node metastasis, TNM staging, lymphatic invasion and vascular invasion. CONCLUSION:
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Authors | Chan Yong Sung, Myoung Won Son, Tae Sung Ahn, Dong Jun Jung, Moon Soo Lee, Moo Jun Baek |
Journal | Journal of the Korean Society of Coloproctology
(J Korean Soc Coloproctol)
Vol. 28
Issue 6
Pg. 315-20
(Dec 2012)
ISSN: 2093-7822 [Print] Korea (South) |
PMID | 23346511
(Publication Type: Journal Article)
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