Utility of antimüllerian hormone level obtained for infertility assessment for alerting to ovarian tumor.

Abstract

BACKGROUND:

Antimüllerian hormone is a marker of ovarian reserve and is now routinely measured in women seeking infertility treatment.

CASE:

A 42-year-old woman, gravida 1, abortus 1, presented with secondary infertility. Obtained originally for assessment of ovarian reserve, an antimüllerian hormone of more than 160 ng/mL raised suspicion for a granulosa cell tumor. A laparoscopic right salpingo-oophorectomy, pelvic washings, dilation and curettage, and peritoneal and omental biopsies were performed. A well-differentiated granulosa cell tumor confined to the right ovary was consistent with stage 1A disease.

CONCLUSION:

As the use of antimüllerian hormone becomes more common for ovarian reserve testing, providers need to maintain an awareness for neoplastic disease with abnormal values.

• Authors: Bryan J Hill, Travis J Morrell, Mallory M Zhang, John M Norian
• Journal: Obstetrics and gynecology (Obstet Gynecol) Vol. 121 Issue 2 Pt 2 Suppl 1 Pg. 454-7 (Feb 2013) ISSN: 1873-233X [Electronic] United States
• PMID: 23344407 (Publication Type: Case Reports, Journal Article)

Chemical References

• Biomarkers, Tumor
• Anti-Mullerian Hormone

Topics

• Adult
• Anti-Mullerian Hormone (blood)
• Biomarkers, Tumor (blood)
• Female
• Granulosa Cell Tumor (blood, diagnosis, surgery)
• Humans
• Infertility, Female (blood)
• Ovarian Neoplasms (blood, diagnosis, surgery)
• Ovariectomy
• Salpingectomy