Abstract | BACKGROUND: METHODS: Seventy five patients ASA physical status I and II, undergoing elective surgery under general anesthesia using endotracheal intubation were enrolled in this prospective, randomized, single-blind study. Patients were randomly divided into 3 groups of 25 patients each: Group (K): (n: 25) Patients in this group were asked to gargle with ketamine 40 mg in 30 ml saline for 60 seconds as repeated smaller attempts, 5 minutes before induction of anesthesia. Group (B) (n: 25): Endotracheal tubes were lubricated with 0.05% betamethasone gel. Group (C) (n: 25): CONTROL GROUP: RESULTS: The incidence and severity of sore throat were significantly lower in group (K) and group (B) than group (C) (p < 0.05) at all time intervals. While there was no significant difference between group (K) and group (B) (p > 0.05). The incidence and severity of cough and hoarseness of voice were significantly lower in group (B) than group (C) and group (k) (p < 0.05) at all time intervals. CONCLUSION: Gargling with ketamine before induction of anesthesia is comparable with application of 0.05% betamethasone gel over the Endotracheal tubes in decreasing postoperative sore throat. In addition, Betmethasone application decreased the incidence and severity of postoperative cough and hoarsness of voice.
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Authors | Ahmad R Shaaban, Sahar M Kamal |
Journal | Middle East journal of anaesthesiology
(Middle East J Anaesthesiol)
Vol. 21
Issue 4
Pg. 513-9
(Feb 2012)
ISSN: 0544-0440 [Print] Lebanon |
PMID | 23327023
(Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Gels
- Glucocorticoids
- Ketamine
- Betamethasone
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Topics |
- Adult
- Anesthesia, General
(methods)
- Betamethasone
(administration & dosage, therapeutic use)
- Cough
(etiology, prevention & control)
- Elective Surgical Procedures
- Female
- Gels
- Glucocorticoids
(administration & dosage, therapeutic use)
- Hoarseness
(etiology, prevention & control)
- Humans
- Incidence
- Intubation, Intratracheal
(adverse effects, methods)
- Ketamine
(administration & dosage, therapeutic use)
- Laryngoscopy
(methods)
- Male
- Middle Aged
- Pharyngitis
(etiology, prevention & control)
- Postoperative Complications
(etiology, prevention & control)
- Prospective Studies
- Severity of Illness Index
- Single-Blind Method
- Young Adult
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