Abstract |
Density functional theory investigations reveal that a cavitand with an introverted aldehyde group not only provides the host-guest interaction for preorganizing the substrate and stabilizing the hemiaminal intermediate, but also acts as an acid/base catalyst in the subsequent dehydration step in its reaction with a primary amine.
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Authors | Lina Xu, Shugui Hua, Shuhua Li |
Journal | Chemical communications (Cambridge, England)
(Chem Commun (Camb))
Vol. 49
Issue 15
Pg. 1542-4
(Feb 21 2013)
ISSN: 1364-548X [Electronic] England |
PMID | 23325093
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Aldehydes
- Amines
- Enzymes
- Ethers, Cyclic
- Gases
- Resorcinols
- cavitand
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Topics |
- Aldehydes
- Amines
(chemistry)
- Catalysis
- Enzymes
(chemistry, metabolism)
- Ethers, Cyclic
(chemistry)
- Gases
(chemistry)
- Hydrogen Bonding
- Resorcinols
(chemistry)
- Thermodynamics
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