[Adjuvant treatment with phenol of aggressive benign and low grade malignant bone tumors in patients with immature skeleton].

Abstract

INTRODUCTION:

The surgical treatment of aggressive benign bone tumors is based on intralesional resection associated with local adjuvant treatment to avoid local relapses. The purpose of this study is to assess the effectiveness of adjuvant treatment with phenol in aggressive, low grade, malignant and benign bone tumors in young patients.

MATERIAL AND METHODS:

We conducted a descriptive retrospective study of 37 patients, 13 girls and 24 boys, with bone tumors. They were treated with curettage and intralesional phenol between January 1989 and January 2006. The study included 35 Campanacci grade III benign tumors and 2 low grade malignant tumors, Enneking IA.

RESULTS:

Minimum follow-up was 5 years. The local relapse rate was 13.5%. Mean age at the time of surgery was 10.7 years (SD +/- 4.4). Mean patient follow-up was 104.9 months (SD +/- 41.9). Mean time between surgery and relapse was 18.8 months (SD +/- 11.81). Complications during the follow-up period occurred in 18.9% of the patients. The MSTS score was 28.7 points (SD +/- 1.7).

DISCUSSION:

The treatment of bone tumors with phenol shows low relapse and complication rates, so it is indicated for the management of locally aggressive bone tumors.

• Authors: V Vaquerizo, J C Abril, A Ramírez, E Montes
• Journal: Acta ortopedica mexicana (Acta Ortop Mex) 2012 Mar-Apr Vol. 26 Issue 2 Pg. 107-11 ISSN: 2306-4102 [Print] Mexico
• Vernacular Title: Tratamiento adyuvante con fenol en tumores óseos benignos agresivos y malignos de bajo grado en pacientes con esqueleto inmaduro.
• PMID: 23323300 (Publication Type: English Abstract, Journal Article)

Chemical References

• Phenol

Topics

• Age Factors
• Bone Neoplasms (surgery, therapy)
• Child
• Combined Modality Therapy
• Female
• Humans
• Male
• Phenol (therapeutic use)
• Retrospective Studies