Abstract |
We investigated the relationships between demographics, lifestyle characteristics, and serum total prostate specific antigen (PSA) concentration and examined the population-based distribution of total PSA by age among 2,246 Korean men with a median age of 45 years. We obtained data about demographic and lifestyle characteristics based on self-reporting using a questionnaire. We also performed physical examinations, anthropometric measurements, and biochemical measurements. The PSA concentration increased with age and there was a significant difference in total PSA concentration between the age groups of 21-60 years and >60 years. Age>60 years, height≥1.8 m, a low frequency of alcohol consumption, and taking nutritional supplements showed a significantly increased odds ratio for increased PSA when 3.0 ng/ mL was chosen as the PSA cut-off level. Smoking status, BMI, percent body fat, diabetes mellitus, fatty liver, herbal medicine use, vitamin use, and diet were not significantly associated with total PSA regardless of the cut-off level. When interpreting a single PSA test, height, alcohol consumption, and nutritional supplement use should be considered, in addition to age.
|
Authors | Hee-Yeon Woo, Hyosoon Park, Min-Jung Kwon, Yoosoo Chang, Seungho Ryu |
Journal | Asian Pacific journal of cancer prevention : APJCP
(Asian Pac J Cancer Prev)
Vol. 13
Issue 11
Pg. 5695-9
( 2012)
ISSN: 2476-762X [Electronic] Thailand |
PMID | 23317241
(Publication Type: Journal Article)
|
Chemical References |
- Prostate-Specific Antigen
|
Topics |
- Adult
- Age Factors
- Aged
- Alcohol Drinking
- Dietary Supplements
- Follow-Up Studies
- Humans
- Life Style
- Male
- Middle Aged
- Prognosis
- Prostate-Specific Antigen
(blood)
- Prostatic Neoplasms
(blood, epidemiology)
- Republic of Korea
(epidemiology)
- Young Adult
|