[A case of gastric neuroendocrine carcinoma with liver metastasis and portal vein invasion successfully treated by S-1 and cisplatin chemotherapy].

Abstract

A 66-year-old man presented with anemia. Endoscopy revealed an elevated lesion with ulceration in the posterior wall of the lesser curvature of the lower gastric body. Endoscopic biopsy demonstrated pathological diagnosis, neuroendocrine carcinoma. A computed tomography scan showed liver metastasis and portal vein invasion. We started chemotherapy with S-1 and cisplatin. After six courses of treatment over seven months, partial response was assessed. We are continuing this chemotherapy now.

• Authors: Shun Kaneko, Yoshihiro Itsui, Masako Hashiguchi, Mamoru Watanabe, Reiko Yoshida, Takumi Akashi, Tsunehito Yauchi, Mamoru Watanabe
• Journal: Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology (Nihon Shokakibyo Gakkai Zasshi) Vol. 110 Issue 1 Pg. 56-63 (Jan 2013) ISSN: 1349-7693 [Electronic] Japan
• PMID: 23303230 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Antimetabolites, Antineoplastic
• Antineoplastic Agents
• Drug Combinations
• S 1 (combination)
• Tegafur
• Oxonic Acid
• Cisplatin

Topics

• Antimetabolites, Antineoplastic (administration & dosage)
• Antineoplastic Agents (administration & dosage)
• Carcinoma, Neuroendocrine (drug therapy, pathology)
• Cisplatin (administration & dosage)
• Drug Combinations
• Humans
• Liver Neoplasms (secondary)
• Male
• Middle Aged
• Neoplasm Invasiveness
• Oxonic Acid (administration & dosage)
• Portal Vein (pathology)
• Stomach Neoplasms (drug therapy, pathology)
• Tegafur (administration & dosage)