Abstract | OBJECTIVES: MATERIALS AND METHODS: The magnetic fluid on the basis of nanoparticles of perovskite manganite was tested in the heating experiments using of alternating magnetic field of frequency 300 kHz and amplitude 7.7 kA/m. Guerin carcinoma was transplanted into the muscle of rat. Magnetic fluid was injected intramuscularly or intratumorally. Temperature was measured by copper-constantan thermocouple. RESULTS: Temperature of magnetic fluid was increased by 56 °C for 10 min of alternating magnetic field action. Administration of magnetic fluid into the muscle followed by alternating magnetic field resulted in the elevation of muscle temperature by 8 °C after 30 min post injection. Temperature of the tumor injected with magnetic fluid and treated by alternating magnetic field was increased by 13.6 °C on the 30 min of combined influence. CONCLUSION:
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Authors | L Bubnovskaya, A Belous, A Solopan, A Podoltsev, I Kondratenko, A Kovelskaya, T Sergienko, S Osinsky |
Journal | Experimental oncology
(Exp Oncol)
Vol. 34
Issue 4
Pg. 336-9
(Dec 2012)
ISSN: 1812-9269 [Print] Ukraine |
PMID | 23302992
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Antineoplastic Agents
- Calcium Compounds
- Manganese Compounds
- Oxides
- manganite
- perovskite
- Manganese
- Lanthanum
- Titanium
- Strontium
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Topics |
- Animals
- Antineoplastic Agents
(pharmacology)
- Calcium Compounds
(pharmacology)
- Female
- Hyperthermia, Induced
(methods)
- Lanthanum
(pharmacology)
- Magnetic Field Therapy
(methods)
- Manganese
(pharmacology)
- Manganese Compounds
(pharmacology)
- Nanoparticles
- Neoplasms, Experimental
(therapy)
- Oxides
(pharmacology)
- Rats
- Strontium
(pharmacology)
- Titanium
(pharmacology)
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