Hypertension terms "dipper" and "non-dipper" are propounded by the change that occurs during ambulatory blood pressure (BP) monitoring. The purpose of this study is to present whether the serum
urotensin II levels are different in patients with dipper and non-dipper
hypertension and to put forward the effects causing this difference, if there are any. Patients recently diagnosed with
hypertension were included in the study. With ambulatory BP monitoring, 81 patients with high BP were divided into two groups, dipper (n = 40) and non-dipper (n = 41). Serum
urotensin II levels were analyzed by ELISA method. Serum
urotensin II levels were higher in patients with non-dipper
hypertension than in patients with dipper
hypertension (204 [106-533] vs. 140 [96-309], P = .004). There was a positive correlation between total systolic BP and serum
urotensin II levels (r = 0.408 and P = .009), but the relation in the non-dipper
hypertension group was not significant (r = 0.194 and P = .2). In conclusion, serum
urotensin II levels were higher in non-dipper HT patients than dipper HT patients. This higher
urotensin II level might be responsible for poor prognoses.