Acute cervical dystonia after the first dose of butamirate citrate.

Abstract

Butamirate citrate is a central-acting antitussive drug and is widely used in clinical practice in childhood. It is thought that to be centrally active antitussive drugs act through receptors in the brainstem to inhibit cough, and these findings were based on the evidence of animal models. Central nervous system adverse effects of cough suppressants are rare and include irritability, lethargy, hallucinations, and dystonic reactions. In this report, we present the first patient who developed cervical dystonia shortly after the first dose of butamirate citrate, and the patient's symptoms improved immediately after a single intramuscular dosage of biperiden.

• Authors: Erhan Bayram, Pakize Karakaya, Yasemin Topcu, Uluc Yis, Semra Hiz
• Journal: Pediatric emergency care (Pediatr Emerg Care) Vol. 29 Issue 1 Pg. 80-1 (Jan 2013) ISSN: 1535-1815 [Electronic] United States
• PMID: 23283272 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antitussive Agents
• Phenylbutyrates
• butamirate

Topics

• Acute Disease
• Antitussive Agents (adverse effects)
• Child, Preschool
• Diagnosis, Differential
• Female
• Humans
• Phenylbutyrates (adverse effects)
• Torticollis (chemically induced)