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Rhodium-catalyzed [2+2+2] cycloaddition of oximes and diynes to give pyridines.

Abstract
Oximes and diynes undergo efficient cycloaddition in the presence of a catalytic amount of a cationic rhodium(I)/dppf complex (see scheme). Spontaneous dehydration of the initially formed cycloadducts leads to the formation of a variety of substituted pyridines in moderate to good yields. The transformation could also be achieved in a one-pot procedure using aldehydes.
AuthorsFen Xu, Chunxiang Wang, Dongping Wang, Xincheng Li, Boshun Wan
JournalChemistry (Weinheim an der Bergstrasse, Germany) (Chemistry) Vol. 19 Issue 7 Pg. 2252-5 (Feb 11 2013) ISSN: 1521-3765 [Electronic] Germany
PMID23281013 (Publication Type: Journal Article)
CopyrightCopyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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