Probable Phaeoacremonium parasiticum as a cause of cavitary native lung nodules after single lung transplantation.

Abstract

Lung nodules after lung transplantation most often represent infection or post-transplant lymphoproliferative disorder in the allograft. Conversely, native lung nodules in single lung transplant recipients are more likely to be bronchogenic carcinoma. We present a patient who developed native lung cavitary nodules. Although malignancy was anticipated, evaluation revealed probable Phaeoacremonium parasiticum infection. Phaeoacremonium parasiticum is a dematiaceous fungus first described as a cause of soft tissue infection in a renal transplant patient. Lung nodules have not been previously described and this is the first case, to our knowledge, of P. parasiticum identified after lung transplantation.

• Authors: S K Shah, P Parto, G A Lombard, M A James, D L Beckles, S Lick, V G Valentine
• Journal: Transplant infectious disease : an official journal of the Transplantation Society (Transpl Infect Dis) Vol. 15 Issue 1 Pg. E9-13 (Feb 2013) ISSN: 1399-3062 [Electronic] Denmark
• PMID: 23279754 (Publication Type: Case Reports, Journal Article)
• Copyright: © 2012 John Wiley & Sons A/S.

Topics

• Aged
• Humans
• Immunocompromised Host
• Lung Diseases, Fungal (diagnosis, microbiology)
• Lung Transplantation
• Male
• Multiple Pulmonary Nodules
• Mycoses (diagnosis, microbiology)
• Phialophora (isolation & purification)
• Tomography Scanners, X-Ray Computed