[A case of long-term survival following combined modality therapy for peritoneal disseminated recurrence of duodenal cancer].

Abstract

A 65-year-old man was diagnosed with primary duodenal cancer and he underwent pancreaticoduodenectomy in June 2006. S-1 was administered as the postoperative adjuvant chemotherapy. A peritoneal disseminated recurrence was diagnosed together with a right reniportal node and right hydronephrosis in February 2007. A ureteral stent was inserted. DOC +S-1 combination therapy was administered from March 2007. Following progression of the recurrence, CDDP+S-1 combination therapy was administered from August 2007. Temporal diminution of the recurrence was achieved with radiotherapy from May to June 2009. Following re-progression of the recurrence, biweekly CPT-11 therapy was administered from February 2010. Weekly PTX therapy was administered from January 2011. The patient died due to progression of the recurrence in June 2011, 5 years after the operation. Our patient maintained a good quality of life and achieved long-term survival by combined modality therapy for peritoneal disseminated recurrence of duodenal cancer.

• Authors: Akira Kabashima, Kensuke Kudo, Toshihiko Nakamura, Mizuki Ninomiya, Takayuki Hamatsu, Hirofumi Hasegawa, Chie Ushijima, Masayuki Kitamura
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 39 Issue 12 Pg. 1969-71 (Nov 2012) ISSN: 0385-0684 [Print] Japan
• PMID: 23267946 (Publication Type: Case Reports, English Abstract, Journal Article)

Topics

• Aged
• Combined Modality Therapy
• Duodenal Neoplasms (pathology, therapy)
• Fatal Outcome
• Follow-Up Studies
• Humans
• Male
• Peritoneal Neoplasms (secondary, therapy)
• Recurrence
• Time Factors