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[Three cases of recurrent bile duct cancer diagnosed and treated by double-balloon endoscopy].

Abstract
Local recurrences often develop after the resection of bile duct cancer. Imaging modalities do not have sufficient sensitivity or specificity to enable the definite diagnosis of recurrent bile duct cancer, and it may be difficult to decide when to start chemotherapeutic treatment. It is difficult to obtain specimens by conventional endoscopy after Roux-Y biliary reconstruction. The double-balloon endoscope(DBE) has 2 balloons: one at the tip of the endoscope and the other at the over- tube. The 2 balloons are inflated alternately and the endoscope can move through the small intestine in a caterpillar-like manner. DBE simplifies the approach to Roux-Y choledochojejunostomy and to obtaining a pathological specimen. Moreover, endoscopic biliary drainage and cholangiography can be performed with the DBE. Recently, the DBE has enabled systemic chemotherapy to be started after obtaining pathological evidence of malignancy, as well as biliary drainage instead of percutaneous transhepatic biliary drainage in cases with recurrent bile duct cancers. Here, we present 3 cases of recurrent bile duct cancer diagnosed and treated by a DBE.
AuthorsKenta Shinozaki, Tetsuo Ajiki, Taro Okazaki, Yuko Yoshida, Sae Murakami, Izuru Ohtsubo, Sachiyo Shirakawa, Masaki Tanaka, Hidehiro Sawa, Tadahiro Goto, Sadaki Asari, Kimihiko Ueno, Hirochika Toyama, Makoto Shinzeki, Masahiro Kido, Ippei Matsumoto, Takumi Fukumoto, Takanobu Hayakumo, Yonson Ku
JournalGan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 39 Issue 12 Pg. 1877-9 (Nov 2012) ISSN: 0385-0684 [Print] Japan
PMID23267916 (Publication Type: Case Reports, English Abstract, Journal Article)
Chemical References
  • Antimetabolites, Antineoplastic
  • Deoxycytidine
  • Gemcitabine
Topics
  • Aged
  • Antimetabolites, Antineoplastic (therapeutic use)
  • Bile Duct Neoplasms (therapy)
  • Deoxycytidine (analogs & derivatives, therapeutic use)
  • Endoscopy
  • Female
  • Humans
  • Male
  • Middle Aged
  • Recurrence
  • Gemcitabine

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