[Current indications of polyvalent immunoglobulins].

Abstract

Polyvalent immunoglobulins have been used for more than 20 years in immune-mediated disorders and humoral immunodeficiency Their use has gradually increased, leading regulatory authorities to issue guidelines on the indications of these costly treatments. Neurological diseases, including autoimmune neuromuscular disorders such as acute and chronic polyradiculoneuropathies and multifocal motor neuropathy, are the main indications of intravenous immunoglobulins. Most patients with these diseases will need long-term maintenance therapy Further research is needed to optimize the use of polyvalent immunoglobulins and to find alternative treatments.

• Authors: Laurent Magy
• Journal: Bulletin de l'Academie nationale de medecine (Bull Acad Natl Med) Vol. 196 Issue 1 Pg. 49-60; discussion 61 (Jan 2012) ISSN: 0001-4079 [Print] Netherlands
• Vernacular Title: Indications actuelles des immunoglobulines polyvalentes.
• PMID: 23259332 (Publication Type: English Abstract, Journal Article)

Chemical References

• Immunoglobulins, Intravenous

Topics

• Autoimmune Diseases of the Nervous System (drug therapy)
• Common Variable Immunodeficiency (drug therapy)
• Humans
• Immunoglobulins, Intravenous (therapeutic use)