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Case report: Transient success using prolonged treatment with miltefosine for a patient with diffuse cutaneous leishmaniasis infected with Leishmania mexicana mexicana.

Abstract
Leishmania sp. is an intracellular parasite that causes a variable degree of clinical manifestations, especially in the skin. We present the case of a 38-year-old male with a chronic history of mucocutaneous disease present since childhood that generated deformity, loss of cartilage in the ears and nose, and scarring that limited his range of motion. The parasite was identified as L. mexicana mexicana. The patient was treated with a 3-month course of oral miltefosine with overwhelming results.
AuthorsAlejandro Ordaz-Farias, Fania Z Muñoz-Garza, Farah K Sevilla-Gonzalez, Ana Arana-Guajardo, Jorge Ocampo-Candiani, Nancy Treviño-Garza, Ingeborg Becker, Adrian Camacho-Ortiz
JournalThe American journal of tropical medicine and hygiene (Am J Trop Med Hyg) Vol. 88 Issue 1 Pg. 153-6 (Jan 2013) ISSN: 1476-1645 [Electronic] United States
PMID23243111 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antiprotozoal Agents
  • Phosphorylcholine
  • miltefosine
Topics
  • Antiprotozoal Agents (therapeutic use)
  • Humans
  • Leishmania mexicana (isolation & purification)
  • Leishmaniasis, Diffuse Cutaneous (drug therapy, parasitology)
  • Phosphorylcholine (analogs & derivatives, therapeutic use)

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