Untreated
bacterial vaginosis is related with many complications for non-pregnant women in reproductive age, most common from them are
vaginal discharge and postoperative
infections. The aim of our investigation was to compare the effectiveness of two therapeutic regimes which consist in
Macmiror/
Macmiror Complex alone and in combination with Feminella Vagi C for treatment of
bacterial vaginosis (BV) and/or mycotic
infection. 117 non-pregnant women with symptoms of vaginal
infection were prospectively enrolled into two groups according their treatment. First group consist 66 women treated with
Macmiror tablets and vaginal capsules followed with local application of Feminella Vagi C, the second group consist 54 women treated with
Macmiror tablets and vaginal capsules only. The impact of treatment on clinical symptoms was observed at the end of medication and 20 days after it. Microbiological testing was repeated 20 days
after treatment. Over than 80% (78.6 divided by 86.7%) of the cases with vaginal
infection (BV and mycotic one) were successfully treated with
Macmiror/
Macmiror Complex. Supplement treatment with Feminella Vagi C lead to higher percentage of clinically recovery (86.7% vs 84.6%), better microbiological cleaning (86.7% vs 82.1%) and longer effect of treatment. Used medication showed higher efficacy against BV than to
fungal infection. According obtained results we may conclude that
bacterial vaginosis was better treated with multipurpose treatment (
Nifuratel, Nistatin and vit. C) than with
Macmiror alone.