Background. Adult
intussusception is a rare entity representing less than 1% of all
intestinal obstructions. Diagnosis of the condition is difficult requiring a high index of suspicion and the utilization of imaging studies, especially CT scans. Diagnostic laparoscopy and/or exploratory
laparotomy can be used as a diagnostic and therapeutic intervention. In over 90% of cases, an underlying lead point is identified. In the patient described here, it was a
gastrointestinal stromal tumor (GIST), a relatively rare mesenchymal
tumor comprising only 0.2-1.0% of the gastrointestinal tract
neoplasms and believed to originate from neoplastic transformation of the interstitial cells of Cajal. GISTs may occur anywhere along the gastrointestinal tract, but most commonly arise in the stomach and small intestine. Literature review revealed only few cases reporting GISTs as a leading point of adult's
intussusception. Case Presentation. In this report, we are presenting a rare case of jejunojejunal
intussusception in a 78-year-old female patient with a GIST located in the terminal jejunum being the leading point, demonstrating the importance of imaging studies, especially CT scan, laparoscopy, and exploratory
laparotomy as diagnostic and therapeutic interventions.