Botulinum toxin a treatment of consecutive esotropia in children.

Abstract

OBJECTIVE:

To assess the outcome of botulinum A toxin (BTXA) to treat surgically overcorrected intermittent exotropia in children.

METHODS:

A retrospective analysis was performed on a series of children with consecutive esotropia treated with BTXA.

RESULTS:

Six children with a mean consecutive esotropia of 21 prism diopters (PD) were treated with BTXA at a mean of 19.8 months following strabismus surgery. Two patients underwent a single injection, three patients 2 injections, and one patient 3 injections. Complications included transient ptosis and a vertical deviation. Mean follow-up from last BTXA injection was 16 months. At last follow-up, 4 of the 6 patients were orthotropic and stereopsis was present in 4 of 5 patients old enough to cooperate with testing. One patient was treated with strabismus surgery following a single BTXA injection.

CONCLUSIONS:

BTXA is an efficacious treatment for consecutive esotropia in children. However, in our series, two-thirds of patients required multiple injections to achieve the desired outcome and one ultimately had an additional strabismus surgery.

• Authors: Natario L Couser, Scott R Lambert
• Journal: Strabismus (Strabismus) Vol. 20 Issue 4 Pg. 158-61 (Dec 2012) ISSN: 1744-5132 [Electronic] England
• PMID: 23211140 (Publication Type: Comparative Study, Journal Article, Research Support, N.I.H., Extramural)

Chemical References

• Anti-Dyskinesia Agents
• Botulinum Toxins

Topics

• Anti-Dyskinesia Agents (administration & dosage)
• Botulinum Toxins (administration & dosage, therapeutic use)
• Child
• Child, Preschool
• Depth Perception (physiology)
• Dose-Response Relationship, Drug
• Esotropia (drug therapy, physiopathology)
• Eye Movements (drug effects, physiology)
• Female
• Follow-Up Studies
• Humans
• Injections, Intramuscular
• Male
• Oculomotor Muscles
• Retrospective Studies
• Treatment Outcome