Weight-loss diet alone or combined with progressive resistance training induces changes in association between the cardiometabolic risk profile and abdominal fat depots.

Abstract

BACKGROUND/AIMS:

A weight-loss diet alone or combined with a progressive resistance training program induced different adaptations on cardiometabolic risk, i.e. regional changes in visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) volume distribution patterns. We hypothesized that a heterogeneous adipose tissue metabolism may exist between visceral fat at different discal levels.

METHODS:

Thirty-four obese women, aged 40-60 years, were randomized to three groups: a control group (n = 9), a diet group (WL; n = 12) with a caloric restriction of 500 kcal/day during 16 weeks, or a diet-plus-resistance-training group (WL+RT; n = 13) with the same caloric restriction and a 16-week resistance training of 2 sessions per week.

RESULTS:

The association pattern between abdominal fat depots and glucose metabolism variables showed a change from the L4-L5 region (preintervention) to VAT L2-L3 and SAT L2-L3 in the WL and WL+RT groups, respectively. It is noteworthy that accumulation of fat in the midthigh was not characterized by a more favorable lipid profile or glucose metabolism.

CONCLUSION:

Our results reinforce the importance of considering L2-L3 images to predict insulin resistance after a weight-loss diet, alone or combined with resistance training.

• Authors: Marisol García-Unciti, Mikel Izquierdo, Fernando Idoate, Esteban Gorostiaga, Ana Grijalba, Francisco Ortega-Delgado, Cristina Martínez-Labari, José M Moreno-Navarrete, Lluis Forga, José Manuel Fernández-Real, Javier Ibáñez
• Journal: Annals of nutrition & metabolism (Ann Nutr Metab) Vol. 61 Issue 4 Pg. 296-304 ( 2012) ISSN: 1421-9697 [Electronic] Switzerland
• PMID: 23208159 (Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2012 S. Karger AG, Basel.

Chemical References

• Biomarkers
• Cholesterol, HDL
• Cholesterol, LDL
• Insulin

Topics

• Adult
• Biomarkers (blood)
• Body Mass Index
• Caloric Restriction
• Cardiovascular Diseases (diet therapy)
• Cholesterol, HDL
• Cholesterol, LDL
• Diet, Reducing
• Energy Intake (physiology)
• Energy Metabolism (physiology)
• Female
• Humans
• Insulin (blood)
• Insulin Resistance
• Intra-Abdominal Fat (metabolism)
• Magnetic Resonance Imaging
• Middle Aged
• Obesity (diet therapy)
• Resistance Training (methods)
• Risk Factors
• Subcutaneous Fat (metabolism)