Abstract | BACKGROUND: METHODS: Patients with moderate to severe stable COPD were randomly divided into 2 groups those who inhaled procaterol before exercise (n=10) and those who did not (control group) (n=11). For 12 weeks, all patients performed their pulmonary rehabilitation exercises at home. We measured the 6-minute walking distance (6MWD) to assess exercise tolerance and used St. George's respiratory questionnaire (SGRQ) to assess health-related quality of life (HRQOL) before and after the 12-week exercise program. RESULTS: Compared to the control group, the group receiving inhaled procaterol showed significant improvement of 6MWD and SGRQ scores. CONCLUSION: Our data suggest that a pulmonary rehabilitation program combined with inhaled procaterol can improve both HRQOL and exercise tolerance in COPD patients.
|
Authors | Makoto Hasegawa, Kunio Dobashi, Takeo Horie, Naoki Wada, Kenji Shirakura |
Journal | Respiratory investigation
(Respir Investig)
Vol. 50
Issue 4
Pg. 135-9
(Dec 2012)
ISSN: 2212-5353 [Electronic] Netherlands |
PMID | 23199977
(Publication Type: Journal Article, Randomized Controlled Trial)
|
Copyright | Copyright © 2012 The Japanese Respiratory Society. Published by Elsevier B.V. All rights reserved. |
Chemical References |
- Adrenergic beta-2 Receptor Agonists
- Procaterol
|
Topics |
- Administration, Inhalation
- Adrenergic beta-2 Receptor Agonists
(administration & dosage)
- Exercise Therapy
- Exercise Tolerance
- Procaterol
(administration & dosage)
- Pulmonary Disease, Chronic Obstructive
(rehabilitation)
- Quality of Life
|