Abstract | BACKGROUND: AIMS: METHODS: We performed a single-center cohort follow-up study of 331 achalasia patients treated with PD. Mean follow-up was 8.9 years, consisting of regular esophageal manometry, timed barium esophagram, and endoscopy. RESULTS: CONCLUSIONS:
Barrett's esophagus is incidentally diagnosed in untreated achalasia patients despite high LES pressures, but is more common after successful treatment, especially in the presence of hiatal herniation. Patients treated for achalasia should be considered for GERD treatment and surveillance of development of Barrett's esophagus, in particular, when they have low LES pressures and a hiatal herniation.
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Authors | I Leeuwenburgh, P Scholten, T J Caljé, R J Vaessen, H W Tilanus, B E Hansen, E J Kuipers |
Journal | Digestive diseases and sciences
(Dig Dis Sci)
Vol. 58
Issue 1
Pg. 244-52
(Jan 2013)
ISSN: 1573-2568 [Electronic] United States |
PMID | 23179142
(Publication Type: Journal Article)
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Chemical References |
- Histamine H2 Antagonists
- Proton Pump Inhibitors
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Topics |
- Adenocarcinoma
(etiology)
- Adult
- Aged
- Aged, 80 and over
- Barrett Esophagus
(etiology)
- Esophageal Achalasia
(complications)
- Esophageal Neoplasms
(etiology)
- Female
- Follow-Up Studies
- Histamine H2 Antagonists
- Humans
- Male
- Middle Aged
- Proton Pump Inhibitors
- Treatment Outcome
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