Abstract | BACKGROUND: AIMS AND OBJECTIVE: The present work was aimed to find out the in vitro efficacy of different topical agents against burn wound pathogens. SETTINGS AND DESIGN: MATERIALS AND METHODS: Multidrug-resistant isolates of gram-positive and gram-negative bacteria were checked for different topical agents. 1% topical agent was mixed with Mueller-Hinton agar. Two microlitres of bacterial suspension adjusted to 0.5 McFarland turbidity standard was spread over the topical agent containing plates. The plates without the topical agent were used as control plates. The plates were incubated for 48 h at 37°C. RESULTS:
SSD (148/148), silver nitrate (148/148) and chlorhexidine (148/148) showed excellent activity against all the pathogens. Neosporin had poor activity against Pseudomonas aeruginosa, (4/44) Proteus spp. (2/4) and group D streptococci (1/4). Betadine did not show activity against the bacterial isolates in the presence of organic matter. Honey did not exert any antimicrobial activity under the study conditions. CONCLUSION:
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Authors | Katara Gunjan, Chamania Shobha, Chitnis Sheetal, Hemvani Nanda, Chitnis Vikrant, Dhananjay Sadashiv Chitnis |
Journal | Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India
(Indian J Plast Surg)
Vol. 45
Issue 2
Pg. 374-8
(May 2012)
ISSN: 1998-376X [Electronic] Germany |
PMID | 23162237
(Publication Type: Journal Article)
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