Uniform polypyrrole nanoparticles with high photothermal conversion efficiency for photothermal ablation of cancer cells.

Abstract

Uniform polypyrrole (PPy) nanoparticles are fabricated from a facile one-step aqueous dispersion polymerization. Owing to their high photothermal conversion efficiency and photostability compared with the well-known Au nanorods, as well as their good colloidal stability and biocompatibility, the resulting PPy nanoparticles can used as a novel promising photothermal ablation coupling agent for targeted treatment of cancer.

• Authors: Zhengbao Zha, Xiuli Yue, Qiushi Ren, Zhifei Dai
• Journal: Advanced materials (Deerfield Beach, Fla.) (Adv Mater) Vol. 25 Issue 5 Pg. 777-82 (Feb 06 2013) ISSN: 1521-4095 [Electronic] Germany
• PMID: 23143782 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Chemical References

• Photosensitizing Agents
• Polymers
• Pyrroles
• polypyrrole

Topics

• HeLa Cells
• Humans
• Hyperthermia, Induced (methods)
• Materials Testing
• Nanoparticles (therapeutic use)
• Neoplasms, Experimental (pathology, therapy)
• Photosensitizing Agents (therapeutic use)
• Phototherapy (methods)
• Polymers (therapeutic use)
• Pyrroles (therapeutic use)
• Treatment Outcome