Abstract | AIM: METHODS: An electronic search was performed in the PubMed Medline, Ovid Medline, ISI Web of Science, Medline, Cochrane Library, Lilacs, Scielo, BBO, Paho and Wholis databases applying the following MeSH terms: " dental caries" OR " tooth demineralization" OR "dental caries susceptibility" OR "dental enamel solubility" AND " salivary proteins and peptides" OR "saliva" AND " proteins". To be eligible for the systematic review, the observational controlled studies had to have groups with and without caries experience. Studies with high risk of bias were excluded. RESULTS: From a total of 188 identified studies, only seven were included in this systematic review. Four studies were classified as "low risk of bias" and three as "moderate risk of bias". Three studies reported a relation between salivary proteins and dental caries. CONCLUSION:
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Authors | Carla Martins, Ana Karla Buczynski, Lucianne Cople Maia, Walter Luiz Siqueira, Gloria Fernanda Barbosa de Araujo Castro |
Journal | Journal of dentistry
(J Dent)
Vol. 41
Issue 1
Pg. 2-8
(Jan 2013)
ISSN: 1879-176X [Electronic] England |
PMID | 23142096
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review, Systematic Review)
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Copyright | Copyright © 2012 Elsevier Ltd. All rights reserved. |
Chemical References |
- Biomarkers
- Salivary Proteins and Peptides
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Topics |
- Biomarkers
(analysis)
- Dental Caries
(diagnosis)
- Dental Caries Susceptibility
(physiology)
- Dental Enamel Solubility
(physiology)
- Humans
- Salivary Proteins and Peptides
(analysis)
- Tooth Demineralization
(diagnosis)
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