In children,
caustic ingestion is due to accidents at home and inadequate storage of
caustic agents. In emergency, it is useful to remove the soiled clothes, rinse the affected area, and prevent
vomiting and feeding.
Caustic ingestion (pH<2 or>12) induces
burns of the upper gastrointestinal tract requiring esophagogastro-duodenoscopy between H12 and H24. Strong
alkalis cause
necrosis with liquefaction of the esophagus, penetrating deeply with a high-risk of perforation. Management of these children requires a specialized care center with an intensive care unit, endoscopic equipment, and a surgical team.
Esophageal stricture is the main complication; no prophylactic treatment (
steroids) is effective.
Strictures occur after the 3rd week, and
barium swallow should be performed by the end of the 1st month.
Stricture are often multiple, long, and tortuous; endoscopic dilatation is difficult with a high-rate of perforation and a low-rate of success. In situ application of
mitomycin C or injection of
triamcinolone could reduce the recurrence rate of
stricture. In recalcitrant or recurrent
strictures, it is recommended to perform an esophageal replacement using a colonic interposition or a gastric tube. Endoscopy should also be performed 15-20years after
caustic ingestion to screen for early neoplastic lesions. Prevention is very important for avoiding
caustic ingestions. Information and education should be given specifically to the parents of toddlers;
caustic products should be stored out of reach of children and they should not be kept with food.