Itraconazole - a potent antifungal drug.

Abstract

Itraconazole is an orally active triazole antifungal drug which has demonstrated a broad spectrum of activity and a favourable pharmacokinetic profile. It is a potent inhibitor of most human fungal pathogens including Aspergillus species.In non comparable clinical trials, Itraconazole was shown to be extremely effective in a wide range of superficial and more serious deep fungal infections when administered once or twice daily. Preliminary findings also indicate that itraconazole, may hold promise for the prophylaxis of opportunistic fungal infections in patients at risk, i.e. women with recurrent vaginal candidiasis, AIDS patients and patients receiving immunosuppressant drugs.

• Authors: N K Panda
• Journal: Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India (Indian J Otolaryngol Head Neck Surg) Vol. 49 Issue 3 Pg. 293-4 (Jul 1997) ISSN: 2231-3796 [Print] India
• PMID: 23119315 (Publication Type: Journal Article)