Abstract |
A 43 year old male patient, known case of multidrug resistant tuberculosis, was prescribed antitubercular drugs: kanamycin, levofloxacin, ethionamide, terizidone, Para-Aminosalicylate Sodium (PAS), pyrazinamide and pyridoxine. After 4 months of treatment, the patient developed a lump in the right breast which was approximately around 3 × 3 cm in size, tender on palpation, and not fixed to the underlying tissues. Ultrasonography (USG) revealed a hypoechoic mass of size 2.5 × 0.92 × 2.6 cm in the right breast region behind the nipple without any infiltration to the deeper structures. Gynecomastia due to ethionamide was suspected and the patient was advised anti-inflammatory drugs for 5 days without any change in drug therapy. The pain subsided; however, the nodule remained. Treatment was continued without any change till the patient stopped using the drugs on his own and without doctor's consent. Within a week of stopping of treatment the nodule also disappeared.
|
Authors | Parveen K Sharma, Rekha Bansal |
Journal | Indian journal of pharmacology
(Indian J Pharmacol)
2012 Sep-Oct
Vol. 44
Issue 5
Pg. 654-5
ISSN: 1998-3751 [Electronic] India |
PMID | 23112434
(Publication Type: Case Reports, Journal Article)
|
Chemical References |
- Antitubercular Agents
- Ethionamide
|
Topics |
- Adult
- Antitubercular Agents
(adverse effects)
- Ethionamide
(adverse effects)
- Gynecomastia
(chemically induced, diagnosis)
- Humans
- Male
- Tuberculosis, Multidrug-Resistant
(drug therapy, pathology)
|