An evaluation of biodegradable synthetic polyurethane foam in patients following septoplasty: a prospective randomized trial.

Abstract

OBJECTIVE:

The purpose of this study is to examine the usability of biodegradable synthetic polyurethane foam (BSPF) after septoplasty by comparing it with Merocel and silicone intranasal splints as packing materials in terms of patient comfort and efficiency.

STUDY DESIGN:

A prospective, unmasked, randomized trial.

SETTING:

A tertiary referral center.

SUBJECTS AND METHODS:

This study was designed to be a prospective, randomized clinical trial. Sixty-eight patients who underwent septoplasty were included in this study. The patients were randomized to receive Merocel, silicone intranasal septal splint (INS), or BSPF after septoplasty. Clinical efficacy on bleeding, pain, and subjective symptoms related to packing materials was evaluated.

RESULTS:

There was a statistically significant difference between the Merocel group and the other 2 groups in terms of bleeding and adhesion. The average score on the pain scale was 2.47 ± 1.01 for BSPF, 3.68 ± 1.27 for INS, and 6 ± 2.21 for Merocel. Scores on general satisfaction scales were 6.95 ± 1.42 for Merocel, 8.44 ± 2.12 for INS, and 8.28 ± 1.88 for BSPF.

CONCLUSION:

The efficacy of BSPF was comparable with that of Merocel and INS. Biodegradable synthetic polyurethane foam significantly reduced pain and patient discomfort during packing and removal, followed by INS, compared with Merocel.

• Authors: Mahmut Sinan Yilmaz, Mehmet Guven, Sultan Sevik Elicora, Recep Kaymaz
• Journal: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery (Otolaryngol Head Neck Surg) Vol. 148 Issue 1 Pg. 140-4 (Jan 2013) ISSN: 1097-6817 [Electronic] England
• PMID: 23112275 (Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)

Chemical References

• Polyurethanes
• Formaldehyde
• polyvinyl alcohol formaldehyde foam
• Polyvinyl Alcohol
• polyurethane foam

Topics

• Absorbable Implants
• Adult
• Evaluation Studies as Topic
• Female
• Follow-Up Studies
• Formaldehyde (pharmacology)
• Humans
• Male
• Materials Testing
• Nasal Septum (surgery)
• Pain Measurement
• Pain, Postoperative (prevention & control)
• Patient Satisfaction
• Polyurethanes (pharmacology)
• Polyvinyl Alcohol (pharmacology)
• Postoperative Hemorrhage (prevention & control)
• Prospective Studies
• Rhinoplasty (adverse effects, methods)
• Risk Assessment
• Tampons, Surgical
• Tertiary Care Centers
• Treatment Outcome
• Young Adult