Abstract | PURPOSE: METHODS: The primary end point was the amount of body weight lost at 1 postoperative year, and secondary end points included other items related to nutritional status such as serum albumin and lymphocyte count, as well as endoscopic examination findings of the remnant stomach and esophagus. Of the 332 patients enrolled, 163 were assigned to the BI group and 169 were randomized to the RY group. RESULTS: The loss in body weight 1 year after surgery did not differ significantly between the BI and RY groups (9.1 % and 9.7 %, respectively, p = 0.39). There were no significant differences in other aspects of nutritional status between the 2 groups. Endoscopic examination 1 year after gastrectomy showed reflux esophagitis in 26 patients (17 %) in the BI group versus 10 patients (6 %) in the RY group (p = 0.0037), while remnant gastritis was observed in 71 patients (46 %) in the BI group versus 44 patients (28 %) in the RY group (p = 0.0013); differences were significant for both conditions. Multivariable analysis showed that the only reconstruction was the independently associated factor with the incidence of reflux esophagitis. CONCLUSIONS:
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Authors | Motohiro Hirao, Shuji Takiguchi, Hiroshi Imamura, Kazuyoshi Yamamoto, Yukinori Kurokawa, Junya Fujita, Kenji Kobayashi, Yutaka Kimura, Masaki Mori, Yuichiro Doki, Osaka University Clinical Research Group for Gastroenterological Study |
Journal | Annals of surgical oncology
(Ann Surg Oncol)
Vol. 20
Issue 5
Pg. 1591-7
(May 2013)
ISSN: 1534-4681 [Electronic] United States |
PMID | 23104705
(Publication Type: Comparative Study, Journal Article, Multicenter Study, Randomized Controlled Trial)
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Chemical References |
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Topics |
- Adenocarcinoma
(blood, surgery)
- Adult
- Aged
- Aged, 80 and over
- Anastomosis, Roux-en-Y
(adverse effects)
- Esophagitis, Peptic
(etiology)
- Female
- Follow-Up Studies
- Gastritis
(etiology)
- Gastroenterostomy
(adverse effects)
- Gastroscopy
- Humans
- Lymphocyte Count
- Male
- Middle Aged
- Multivariate Analysis
- Nutritional Status
- Serum Albumin
(metabolism)
- Stomach Neoplasms
(blood, surgery)
- Weight Loss
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