[Ventilation in acute respiratory distress. Lung-protective strategies].

Abstract

Ventilation of patients suffering from acute respiratory distress syndrome (ARDS) with protective ventilator settings is the standard in patient care. Besides the reduction of tidal volumes, the adjustment of a case-related positive end-expiratory pressure and preservation of spontaneous breathing activity at least 48 h after onset is part of this strategy. Bedside techniques have been developed to adapt ventilatory settings to the individual patient and the different stages of ARDS. This article reviews the pathophysiology of ARDS and ventilator-induced lung injury and presents current evidence-based strategies for ventilator settings in ARDS.

• Authors: C S Bruells, R Rossaint, R Dembinski
• Journal: Medizinische Klinik, Intensivmedizin und Notfallmedizin (Med Klin Intensivmed Notfmed) Vol. 107 Issue 8 Pg. 596-602 (Nov 2012) ISSN: 2193-6226 [Electronic] Germany
• Vernacular Title: Beatmung beim akuten Lungenversagen. Lungenprotektive Strategien.
• PMID: 23093038 (Publication Type: Journal Article, Review)

Topics

• Air Pressure
• Critical Care (methods)
• Evidence-Based Medicine
• Humans
• Positive-Pressure Respiration (methods)
• Pulmonary Alveoli (physiopathology)
• Pulmonary Gas Exchange (physiology)
• Respiratory Distress Syndrome (mortality, therapy)
• Respiratory Paralysis (mortality, physiopathology, therapy)
• Risk Factors
• Tidal Volume (physiology)
• Ventilator-Induced Lung Injury (mortality, physiopathology, prevention & control)