A case of intraperitoneal immunoglobulin G4-related inflammatory pseudotumor.

Abstract

The term inflammatory pseudotumor (IPT) has been used to describe inflammatory and fibrosing tumoral processes of an undetermined cause that may involve a variety of organ system. IgG4-related disease is a newly recognized fibroinflammatory condition characterized by IgG4-producing plasma cell expansion in affected organs and, often but not always, elevated serum IgG4 concentrations. IgG4-related IPTs, a subtype of IPT, are characterized by dense infiltration of IgG4-positive plasma cells and stromal fibrosis. The association between inflammatory pseudotumor and IgG4 was first reported with a regard to sclerosing pancreatitis. Despite there are many reports on intraperitoneal IPTs including both cellular and lymphoplasmacytic type, only a few cases have been confirmed to be IgG4-related. We experienced a case of intraperitoneal IgG4-related inflammatory pseudotumor in an 83-year-old woman presenting with epigastric pain and malaise. Surgical specimens revealed an IgG4-related inflammatory pseudotumor.

• Authors: In Ho Moh, Jin Bae Kim, Su Rin Shin, Sung Won Jung, Sang Hoon Park, Jeong Won Kim, Mi Kyung Shin, Myung Seok Lee
• Journal: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi (Korean J Gastroenterol) Vol. 60 Issue 4 Pg. 258-61 (Oct 2012) ISSN: 2233-6869 [Electronic] Korea (South)
• PMID: 23089913 (Publication Type: Case Reports, Journal Article)

Chemical References

• Immunoglobulin G
• C-Reactive Protein

Topics

• Aged, 80 and over
• C-Reactive Protein (analysis)
• Female
• Granuloma, Plasma Cell (diagnosis, pathology, surgery)
• Humans
• Immunoglobulin G (blood)
• Plasma Cells (metabolism)
• Positron-Emission Tomography
• Tomography, X-Ray Computed