Pseudomonas aeruginosa, an emerging pathogen among burn patients in Kurdistan Province, Iran.
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| Abstract |
This study was conducted to determine the incidence of Pseudomonas aeruginosa infections among burn patients at Tohid Hospital, Iran. A total of 176 clinical specimens were obtained from 145 burn patients admitted to the burn unit of Tohid Hospital to detect the presence of P. aeruginosa. Antimicrobial susceptibility testing was conducted to detect extended spectrum beta-lactamase (ESBL) producing P. aeruginiosa using Clinical and Laboratory Standards Institute guidelines with the double disc synergy test (DDST). A polymerase chain reaction was used to detect PER-1 and OXA-10 among the isolates. The mean age, total body surface area and length of hospital stay among patients were 29 years, 37.7%, and 10 days, respectively. Kerosene was the commonest cause of burn (60%), followed by gas (30%). During the study, P. aeruginosa was detected in 100 isolates. The antibiotics they were most commonly resistant to were cefotaxime, ceftriaxone and ciprofloxacin. Of the 100 P. aeroginusa isolates, 28% were positive for ESBL production with the DDST, 48% and 52% were PER-1 and OXA-10 producers, respectively. The high frequency of PER-1 and OXA-10 producers at this hospital is of concern considering their potential spread among burn patients.
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| Authors | Enayat Kalantar, Shadi Taherzadeh, Tayeb Ghadimi, Fariborz Soheili, Heiman Salimizand, Alireza Hedayatnejad |
| Journal | The Southeast Asian journal of tropical medicine and public health (Southeast Asian J Trop Med Public Health) Vol. 43 Issue 3 Pg. 712-7 (May 2012) ISSN: 0125-1562 [Print] Thailand |
| PMID | 23077851 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't) |
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