Abstract | OBJECTIVE: SUBJECTS AND METHODS: Xe-CT was performed before LDL-A in 4 dialysis patients with ASO (3 males and 1 female). LDL-A was then performed once a week 10 times. After the completion of LDL-A treatment, Xe-CT was performed again to observe changes in CBF. RESULTS: Before treatment, CBF in the 4 patients was lower than that in the general population in the same age group. After LDL-A treatment, CBF was improved. The improvement was observed in the cerebral cortex rather than the basal ganglia. The grade of improvement and improved cerebral region varied among the patients. CONCLUSION: It was suggested that LDL-A may improve not only lower limb blood flow but also CBF. However, further investigation is necessary with regard to the influence of CBF improvement on the brain function and clinical application. The reported results need to be confirmed in larger studies.
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Authors | Fumitaka Nakajima, Satoshi Morimoto, Takatomi Yurugi, Yoshihumi Amari, Yuko Kasuno, Masayoshi Fukui, Yoshiyuki Furumatsu, Tetsuya Kitamura |
Journal | The International journal of artificial organs
(Int J Artif Organs)
Vol. 35
Issue 11
Pg. 981-5
(Nov 2012)
ISSN: 1724-6040 [Electronic] United States |
PMID | 23065872
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Aged
- Arteriosclerosis Obliterans
(complications, physiopathology, therapy)
- Blood Component Removal
- Cerebral Infarction
(prevention & control)
- Cerebrovascular Circulation
(physiology)
- Cohort Studies
- Female
- Humans
- Kidney Failure, Chronic
(complications, physiopathology, therapy)
- Lipoproteins, LDL
- Male
- Middle Aged
- Pilot Projects
- Renal Dialysis
- Treatment Outcome
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