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Pantothenate - kinase associated neurodegeneration.

Abstract
Neurodegeneration with brain iron accumulation is a group of disorders, the commonest of which is PKAN (Pantothenate kinase associated neurodegeneration). We present here, a case of 18 year old boy with progressive dementia, pyramidal and extrapyramidal involvement, dysarthria, seizures and myoclonus. The patient was diagnosed as PKAN (formerly Hallervorden Spatz disease) after "eye of tiger" appearance on neuro-imaging.
AuthorsAlpana Parmar, Shruti Khare, Vipul Srivastav
JournalThe Journal of the Association of Physicians of India (J Assoc Physicians India) Vol. 60 Pg. 74-6 (Apr 2012) ISSN: 0004-5772 [Print] India
PMID23029753 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Cholinergic Antagonists
  • Muscle Relaxants, Central
Topics
  • Adolescent
  • Cholinergic Antagonists (therapeutic use)
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Muscle Relaxants, Central (therapeutic use)
  • Pantothenate Kinase-Associated Neurodegeneration (diagnosis, drug therapy)

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