Bioactive glass S53P4 in mastoid obliteration surgery for chronic otitis media and cerebrospinal fluid leakage.

Abstract

OBJECTIVES:

We evaluated the results of cases of chronic otitis media treated with mastoid obliteration surgery using bioactive glass S53P4.

METHODS:

Twenty-five patients with chronic otitis media and 1 patient with cerebrospinal fluid leakage without chronic infection were treated with bioactive glass S53P4. Twenty patients had had previous surgery because of chronic otitis media with or without cholesteatoma. A mastoid obliteration was performed with bioactive glass S53P4 granules and a musculoperiosteal flap with or without bone paté. In 2 patients with a bony dehiscence at the middle cranial fossa, a bioactive glass plate was used to support the protruding dura. In addition, in 3 patients, occlusion of a dural fistula was needed The median follow-up period was 34.5 months (range, 1 to 182 months).

RESULTS:

Excluding the 2 patients with only 1 month of follow-up at our department, 96% of the patients had a dry, safe ear or only intermittent otorrhea. In 92% of the patients, the objective of achieving a smaller or nonexistent cavity was achieved.

CONCLUSIONS:

Bioactive glass S53P4 is a noteworthy material in mastoid obliteration surgery.

• Authors: Jussi Sarin, Reidar Grénman, Kalle Aitasalo, Jaakko Pulkkinen
• Journal: The Annals of otology, rhinology, and laryngology (Ann Otol Rhinol Laryngol) Vol. 121 Issue 9 Pg. 563-9 (Sep 2012) ISSN: 0003-4894 [Print] United States
• PMID: 23012893 (Publication Type: Journal Article)

Chemical References

• Bone Substitutes
• bioactive glass S53P4

Topics

• Adult
• Aged
• Bone Substitutes
• Cerebrospinal Fluid Leak
• Cerebrospinal Fluid Rhinorrhea (surgery)
• Cholesteatoma, Middle Ear (surgery)
• Chronic Disease
• Female
• Glass
• Humans
• Male
• Mastoid (surgery)
• Middle Aged
• Otitis Media (surgery)
• Otologic Surgical Procedures (adverse effects, methods)