Treatment of acute colonic pseudoobstruction (Ogilvie's syndrome) with cisapride.

Abstract

A 73-yr-old white woman admitted with lobar pneumonia and congestive heart failure developed progressive colonic pseudoobstruction (Ogilvie's syndrome) 2 days after admission which was unrelieved by diatrizoate meglumine (Gastrografin, Squibb Canada, Montreal) enema and rectal tube. Cisapride, a new gastrointestinal prokinetic agent, was administered intravenously with full resolution of the syndrome. To the authors' knowledge, this is the first reported case of successful treatment of acute colonic pseudoobstruction with cisapride.

• Authors: C MacColl, K L MacCannell, B Baylis, S S Lee
• Journal: Gastroenterology (Gastroenterology) Vol. 98 Issue 3 Pg. 773-6 (Mar 1990) ISSN: 0016-5085 [Print] United States
• PMID: 2298376 (Publication Type: Case Reports, Journal Article)

Chemical References

• Drugs, Investigational
• Piperidines
• Serotonin Antagonists
• Cisapride

Topics

• Acute Disease
• Aged
• Cisapride
• Colonic Diseases (diagnosis, drug therapy, pathology)
• Colonic Pseudo-Obstruction (diagnosis, drug therapy, pathology)
• Drug Evaluation
• Drugs, Investigational (administration & dosage, therapeutic use)
• Female
• Humans
• Infusions, Intravenous
• Intestinal Pseudo-Obstruction (drug therapy)
• Piperidines (administration & dosage, therapeutic use)
• Serotonin Antagonists (administration & dosage, therapeutic use)
• Time Factors