Opsoclonus-myoclonus syndrome following influenza a infection.

Abstract

A 60-year-old woman developed opsoclonus-myoclonus syndrome (OMS) a week after being diagnosed with influenza A infection by a rapid antigen test. She had no loss of consciousness. Opsoclonus, myoclonus, and truncal ataxia were noted. Two weeks after treatment with intravenous immunoglobulin and corticosteroids, her opsoclonus, myoclonus, and truncal ataxia disappeared. No malignant tumors were detected during the 3-year follow-up period. There has been no previous report of postinfectious OMS following confirmed influenza A infection. OMS without a loss of consciousness has been reported to be statistically less common in cases of non-paraneoplastic OMS. This finding was consistent with the present patient's clinical manifestations.

• Authors: Akihiko Morita, Masaki Ishihara, Satoshi Kamei, Hiroshi Ishikawa
• Journal: Internal medicine (Tokyo, Japan) (Intern Med) Vol. 51 Issue 17 Pg. 2429-31 ( 2012) ISSN: 1349-7235 [Electronic] Japan
• PMID: 22975562 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Adrenal Cortex Hormones
• Immunoglobulins, Intravenous

Topics

• Adrenal Cortex Hormones (therapeutic use)
• Female
• Follow-Up Studies
• Humans
• Immunoglobulins, Intravenous (therapeutic use)
• Immunotherapy
• Influenza A virus
• Influenza, Human (complications)
• Middle Aged
• Opsoclonus-Myoclonus Syndrome (diagnosis, drug therapy, etiology)
• Treatment Outcome