The late recurrence of ganglioneuroma 21 years after initial presentation with neuroblastoma.

Abstract

A 3-year-old boy presented with tumors in the adrenal gland and the right orbit, and was diagnosed with neuroblastoma. After chemotherapy, the tumors were resected and the pathological diagnoses of ganglioneuroblastoma in the adrenal gland and ganglioneuroma in the orbit were made. The tumor relapsed at the intracranial dura mater 21 years after the initial diagnosis, and was diagnosed as ganglioneuroma from a biopsied sample. This case is very unique in that ganglioneuroma matured from ganglioneuroblastoma or neuroblastoma had the late recurrence with 21 years of tumor dormancy.

• Authors: Yoshiko Okita, Yoshitaka Narita, Akihiko Yoshida, Yasuji Miyakita, Makoto Ohno, Masanao Saio, Naoki Yoshimi, Soichiro Shibui
• Journal: Pediatric hematology and oncology (Pediatr Hematol Oncol) Vol. 29 Issue 7 Pg. 647-51 (Oct 2012) ISSN: 1521-0669 [Electronic] England
• PMID: 22966943 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Child, Preschool
• Disease Progression
• Ganglioneuroblastoma (diagnosis, drug therapy, pathology)
• Ganglioneuroma (diagnosis, drug therapy, pathology)
• Humans
• Magnetic Resonance Imaging
• Male
• Neuroblastoma (diagnosis, drug therapy, pathology)
• Recurrence