Abstract | BACKGROUND: METHODS: An open parallel prospective longitudinal study involving two centers was designed to compare patients with PPA submitted to SLT (1 h/week for 11 months) with patients receiving no therapy. Twenty patients were enrolled and undertook baseline language and neuropsychological assessments; among them, 10 received SLT and 10 constituted an age- and education-matched historical control group. The primary outcome measure was the change in group mean performance on the Snodgrass and Vanderwart naming test between baseline and follow-up assessments. RESULTS: Intervention and control groups did not significantly differ on demographic and clinical variables at baseline. A mixed repeated measures ANOVA revealed a significant main effect of therapy (F(1,18) = 10.763; p = 0.005) on the performance on the Snodgrass and Vanderwart naming test. CONCLUSION: Although limited by a non-randomized open study design with a historical control group, the present study suggests that SLT may have a benefit in PPA, and it should prompt a randomized, controlled, rater-blind clinical trial.
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Authors | Luísa Farrajota, Carolina Maruta, João Maroco, Isabel Pavão Martins, Manuela Guerreiro, Alexandre de Mendonça |
Journal | Dementia and geriatric cognitive disorders extra
(Dement Geriatr Cogn Dis Extra)
Vol. 2
Issue 1
Pg. 321-31
(Jan 2012)
ISSN: 1664-5464 [Electronic] Switzerland |
PMID | 22962556
(Publication Type: Journal Article)
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